Transcriptional regulation of adaptive NK and CD8 T cell responses [RNA-Seq]

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UID: 10379

Author(s): Lau, Colleen M.*, Sun, Joseph C.* * MSK affiliated

Publisher(s): Memorial Sloan Kettering Cancer Center

Description: Natural killer (NK) cells are innate lymphocytes that possess features of adaptive immunity such as clonal expansion and generation of long-lived memory. Here we look at transcriptional profiles of NK cells throughout several time points during MCMV infection, ex-vivo cytokine stimulation, and/or deficiency of key transcription factors such as STAT4, STAT1, and Runx1. In addition, we profile parallel time points of MCMV-specific CD8 T cells during infection and memory formation.

Part of a SuperSeries accession comprised of:
Transcriptional and epigenetic regulation of adaptive NK cell responses [ChIP-Seq]
Transcriptional regulation of adaptive NK and CD8 T cell responses [RNA-Seq]
Epigenetic control of innate and adaptive immune memory [ATAC-Seq]

Subject of Study

Subject(s)

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