TMB and Immunotherapy (MSKCC, Nat Genet 2019): Genomic and survival data from 1661 tumor-normal pairs from 1661 patients with various cancer types sequenced with the MSK-IMPACT assay.
UID: 10452
Publisher(s): Memorial Sloan Kettering Cancer Center- Description
- This dataset contains summary data visualizations and clinical data from a broad sampling of 1,661 samples of across multiple cancer types showing tumor mutational load and survival following immunotherapy from 1,661 patients. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), mutation count, patient demographics, survival status, tumor sample details, Drug Type Gene Panel, Metastatic Site, Primary Tumor Site, Sample coverage, Somatic Status, and TMB Score.
Acral Melanoma
Adenocarcinoma, NOS
Anaplastic Oligodendroglioma
Anorectal Mucosal Melanoma
Astrocytoma
Bladder Adenocarcinoma
Bladder Urothelial Carcinoma
Bladder Squamous Cell Carcinoma
Invasive Breast Carcinoma
Breast Invasive Cancer, NOS
Breast Invasive Carcinoma, NOS
Clear Cell Odontogenic Carcinoma
Renal Clear Cell Carcinoma
Chromophobe Renal Cell Carcinoma
Colon Adenocarcinoma
Colorectal Adenocarcinoma
Cutaneous Squamous Cell Carcinoma
Cancer of Unknown Primary
Cancer of Unknown Primary, NOS
Desmoplastic Melanoma
Esophagogastric Adenocarcinoma
Esophageal Poorly Differentiated Carcinoma
Esophageal Adenocarcinoma
Esophageal Squamous Cell Carcinoma
Mucosal Melanoma of the Esophagus
FH-Deficient Renal Cell Carcinoma
Glioblastoma
Glioblastoma Multiforme
Adenocarcinoma of the Gastroesophageal Junction
Gliosarcoma
High-Grade Glioma, NOS
Head and Neck Mucosal Melanoma
Head and Neck Neuroendocrine Carcinoma
Head and Neck Squamous Cell Carcinoma
Head and Neck Squamous Cell Carcinoma of Unknown Primary
Hypopharynx Squamous Cell Carcinoma
Breast Invasive Ductal Carcinoma
Breast Invasive Lobular Carcinoma
Intestinal Type Stomach Adenocarcinoma
Low-Grade Glioma, NOS
Lung Adenocarcinoma
Lung Adenosquamous Carcinoma
Large Cell Neuroendocrine Carcinoma
Pleomorphic Carcinoma of the Lung
Lung Squamous Cell Carcinoma
Larynx Squamous Cell Carcinoma
Mucinous Adenocarcinoma of the Colon and Rectum
Breast Mixed Ductal and Lobular Carcinoma
Melanoma
Mucinous Stomach Adenocarcinoma
Renal Mucinous Tubular Spindle Cell Carcinoma
Melanoma of Unknown Primary
Neuroendocrine Carcinoma, NOS
Neuroendocrine Tumor, NOS
Nasopharyngeal Carcinoma
Non-Small Cell Lung Cancer
Poorly Differentiated Non-Small Cell Lung Cancer
Oral Cavity Squamous Cell Carcinoma
Oligodendroglioma
Odontogenic Carcinoma
Head and Neck Carcinoma, Other
Oropharynx Squamous Cell Carcinoma
Primary CNS Melanoma
Poorly Differentiated Carcinoma, NOS
Papillary Renal Cell Carcinoma
Renal Cell Carcinoma
Rectal Adenocarcinoma
Sarcomatoid Carcinoma of the Lung
Sarcomatoid Carcinoma of the Urinary Bladder
Small Cell Bladder Cancer
Squamous Cell Carcinoma, NOS
Renal Clear Cell Carcinoma with Sarcomatoid Features
Small Cell Carcinoma of Unknown Primary
Cutaneous Melanoma
Sinonasal Squamous Cell Carcinoma
Poorly Differentiated Carcinoma of the Stomach
Plasmacytoid/Signet Ring Cell Bladder Carcinoma
Signet Ring Cell Adenocarcinoma of the Colon and Rectum
Signet Ring Cell Carcinoma of the Stomach
Stomach Adenocarcinoma
Translocation-Associated Renal Cell Carcinoma
Tubular Stomach Adenocarcinoma
Urachal Adenocarcinoma
Urethral Adenocarcinoma
Urethral Urothelial Carcinoma
Undifferentiated Malignant Neoplasm
Uveal Melanoma
Unclassified Renal Cell Carcinoma
Mucosal Melanoma of the Urethra
Urethral Squamous Cell Carcinoma
Upper Tract Urothelial Carcinoma
Mucosal Melanoma of the Vulva/Vagina
- Access Restrictions
-
Free to All
- Access Instructions
- This cBioPortal for Cancer Genomics dataset is publicly available for viewing online as tables, graphs, and/or charts. The data is also available for download in its entirety as a tarball or as individual TSV (tab separated value) files. Some features are only available by logging in with a Google or Microsoft account. These feautes include storing your virtual studies and groups which allows you to access your studies and groups from any computer, and to allow cBioPortal to remember your study view charts preferences for each study (i.e. order of the charts, type of charts and visibility). Login is optional and not required to access any of the other features of cBioPortal.
- Associated Publications
- Data Type
- Software Used
- Dataset Format(s)
- TAR
- Data Tool(s)
-
MSK-IMPACT
- Dataset Size
- 2.3 MB
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