RNA-seq analysis in NRG1 and enzalutamide treated 22Pc-EP cell line

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UID: 10507

Author(s): Zhang, Zeda, Sawyers, Charles L.* * MSK affiliated

Description: Author summary from Gene Expression Omnibus: "Transcriptome prolifing analysis was performed in 22Pc-EP cells to identify differentially regulated genes by enzalutamide and NRG1. 22Pc-EP cells were treated with androgen receptor inhibition (enzalutamide) or a HER3 ligand NRG1 for 48hrs."

The data is from a study on tumor microenvironment-derived NRG1 promotes antiandrogen resistance in prostate cancer.

Subject of Study

Subject(s)

OncoTree Cancer Type(s)

Prostate

Access via GEO

Accession #: GSE147976

Access via SRA
RNA Sequence reads for 21 samples
Accession #: SRP255006

Access via BioProject
Additional information about overall initiative.
Accession #: PRJNA622705
Access Restrictions: Free to All
Access Instructions: The NCBI Gene Expression Omnibus database provides open access to these files.
Associated Publications: Zhang Z, Karthaus W, Lee Y, et al. Tumor microenvironment-derived NRG1 promotes antiandrogen resistance in prostate cancer. Cancer Cell. 2020; 38(2):279-296.e9.
Data Type: Genomic
Equipment Used: Illumina NovaSeq 6000
Dataset Format(s): CSV, XLSX
Dataset Size: 1.2 Mb (CSV), 55.0 Mb (XLSX), 23.7 GB (SRA)

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