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RNA-seq analysis in NRG1 and enzalutamide treated 22Pc-EP cell line

UID: 10507

Author(s): Zhang, Zeda, Sawyers, Charles L.* * MSK affiliated

Author summary from Gene Expression Omnibus: "Transcriptome prolifing analysis was performed in 22Pc-EP cells to identify differentially regulated genes by enzalutamide and NRG1. 22Pc-EP cells were treated with androgen receptor inhibition (enzalutamide) or a HER3 ligand NRG1 for 48hrs."

The data is from a study on tumor microenvironment-derived NRG1 promotes antiandrogen resistance in prostate cancer.
Subject of Study
OncoTree Cancer Type(s)
Access via GEO

Accession #: GSE147976

Access via SRA

RNA Sequence reads for 21 samples
Accession #: SRP255006

Access via BioProject

Additional information about overall initiative.
Accession #: PRJNA622705

Access Restrictions
Free to All
Access Instructions
The NCBI Gene Expression Omnibus database provides open access to these files.
Associated Publications
Data Type
Equipment Used
Illumina NovaSeq 6000
Dataset Format(s)
Dataset Size
1.2 Mb (CSV), 55.0 Mb (XLSX), 23.7 GB (SRA)
Data Catalog Record Updated