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Histiocytosis Cobimetinib (MSK, Nature 2019): Targeted and whole exome sequencing of 52 histiocytosis tumor/normal pairs

UID: 10585

Publisher(s): Memorial Sloan Kettering Cancer Center

Description
This dataset contains the summary data visualizations and clinical data from targeted and whole exome sequencing of 52 histiocytosis tumor/normal pairs from 18 patients. Clinical data includes: Number of Samples Per Patient, Mutation Count, Fraction Genome Altered, Diagnosis Age, Sex, Primary/Metastasis Sample Type, Any dose reduction, Disease at Diagnosis, Duration of Treatment (Months), ECOG status, Evaluable for PET?, Evaluable for RECIST?, Immunosuppression, Interferon Alpha Therapy, Kinase Inhibitor, MAPK Pathway Alteration. The plaintext components of the dataset can be downloaded as a tar file. The clinical data can be downloaded as a tsv file. The dataset includes copy-number segment data downloadable as .seg files and viewable via the Integrative Genomics Viewer.
Subject of Study
Subject(s)
OncoTree Cancer Type(s)
Erdheim-Chester Disease
Histiocytic and Dendritic Cell Neoplasms
Langerhans Cell Histiocytosis
Rosai-Dorfman Disease
Access Restrictions
Free to All
Access Instructions
This cBioPortal for Cancer Genomics dataset is publicly available for viewing in tables or, for copy-number segments, via integrated IGV application. The data is also available for download in its entirety as a tarball or as individual TSV (tab separated value) or SEG files. Some features are only available by logging in with a Google or Microsoft account. These features include storing your virtual studies and groups which allows you to access your studies and groups from any computer, and to allow cBioPortal to remember your study view charts preferences for each study (i.e. order of the charts, type of charts and visibility). Login is optional and not required to access any of the other features of cBioPortal.
Associated Publications
Data Type
Software Used
Integrative Genomics Viewer (IGV)
Dataset Format(s)
TSV, TAR, SEG
Dataset Size
97.2 KB (TAR), 17KB (TSV), 42 KB (SEG)
Data Catalog Record Updated
2021-06-17