Whole-exome sequencing of metaplastic carcinoma of the breast
UID: 10635
Publisher(s): Memorial Sloan Kettering Cancer Center- Description
- Description from BioProject: "Whole-exome sequencing of metaplastic carcinoma of the breast"
Description from Metadata Record DOI for the associated manuscript: "The related study sought to determine the frequency of genetic alterations affecting TERT in a cohort of 60 metaplastic breast cancers (MBCs) with distinct predominant metaplastic components (squamous, 23%; spindle, 27%; osseous, 8%; chondroid, 42%), and to compare the repertoire of genetic alterations of MBCs according to the presence of TERT promoter hotspot mutations or gene amplification.
Type of data: whole exome sequencing, histologic images
Subject of data: Homo sapiens
Sample size: 60 primary MBCs
Population characteristics: Archived tumours classified as metaplastic breast cancer with representative materials available were selected for this study and retrospectively analysed." - Local Expert
Carcinoma with Chondroid Metaplasia
Carcinoma with Osseous Metaplasia
Epithelial Type Metaplastic Breast Cancer
Metaplastic Breast Cancer
Mixed Type Metaplastic Breast Cancer
Metaplastic Squamous Cell Carcinoma
-
Access via BioProject
Access to Information about the Research
Accession #: PRJNA317538Access via SRAWhole Exome Sequencing for 35 Samples
Accession #: SRP073692 - Access Restrictions
-
Free to All
- Access Instructions
- The NCBI SRA and BioProject databases provide open access to these files.
- Associated Publications
- Data Type
- Equipment Used
- Software Used
- Dataset Format(s)
- SRA, BAM
- Data Tool(s)
-
WXS
- Dataset Size
- 551.9 GB (BAM), 552 Gb (SRA)
Do you have or know of a dataset that should be added to the catalog? Let us know!