DOT1L inhibitors block abnormal self-renewal induced by cohesin loss

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UID: 10643

Publisher(s): Medical College of Wisconsin

Description: This Dataset is a SuperSeries composed of the following SubSeries:

GSE140359 DOT1L inhibitors block abnormal self-renewal induced by cohesin loss [RNA-seq]

GSE140360 DOT1L inhibitors block abnormal self-renewal induced by cohesin loss [ChIP-seq]

Data stored in this GEO relates to Acute myeloid leukemia (AML) and DOT1L inhibitors stored in two sequence formats.

Subject of Study

Subject(s)

OncoTree Cancer Type(s)

Acute Myeloid Leukemia

Access via GEO
TAR of BigWig and GTF files of expression profiling and genome binding/occupancy profiling by high throughput sequencing
Accession #: GSE140361

Access via BioProject
Additional information about overall initiative
Accession #: PRJNA589333
Access Restrictions: Free to All
Access Instructions: The NCBI Gene Expression Omnibus and BioProject databases provide open access to these files.
Associated Publications: Heimbruch K, Fisher J, Stelloh C, et al. DOT1L inhibitors block abnormal self-renewal induced by cohesin loss. Scientific Reports. 2021; 11:7288.
Data Type: Genomic
Equipment Used: Illumina NextSeq 500
Dataset Format(s): TAR, BIGWIG, GTF
Dataset Size: 3.6 GB

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