Analysis of genomic aberrations by array comparative genomic hybridization (aCGH) of tumor tissues of mice after 12 months on CD-HFD (n= 9) or 12 months on CD-HFD plus 8 weeks treatment with α-PD-1 (n= 12)

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UID: 10666

Author(s): Pfister, Dominik, Heikenwälder, Mathias, Unger, Kristian

Description: Summary from the GEO: "Genomic DNA was extracted from tumors that developed in C57BL/6 mice fed with CD-HFD for 12 months alone or fed with CD-HFD for 12 months followed by 8 weeks of treatment with anti-PD-1. DNA extracted from five pooled tail-clips of C57BL/6 mice was used as reference DNA."

Overall design from the GEO: "the tumor profiles of 9 CD-HFD only mice was compared to that of 12 CD-HFD/anti-PD1-treated mice."

Subject of Study

Subject(s)

Access via GEO
Plain Text Data of genome variation profiling by array
Accession #: GSE144875

Access via BioProject
Additional information about overall initiative
Accession #: PRJNA605198
Access Restrictions: Free to All
Access Instructions: The NCBI Gene Expression Omnibus, and BioProject databases provide open access to these files.
Associated Publications: Pfister D, Núñez N, Pinyol R, et al. NASH limits anti-tumour surveillance in immunotherapy-treated HCC. Nature. 2021; 592(7854):450-456.
Data Type: Genomic
Equipment Used: Agilent-041078 mouse_60k_MH

Agilent-081060 mouse_60k_array
Mouse MicroArray from Agilent
Dataset Format(s): Plain Text
Dataset Size: 378 MB

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