Examining alterations in gene expression of LNCaP-Ctrl (PSMA +ve) vs LNCaP-KD (PSMA -ve) cells
UID: 10691
Publisher(s): GCMI, Massachusetts General Hospital- Description
- Summary from the GEO: "The biological role of PSMA, a biomarker expressed in prostate cancer and by the neovasculature of solid tumors, remains unknown. Although PSMA processes folates in our duodenum, and in the brain cleaves NAAG to control neuronal signaling, little is known about its role in cancer.
We used microarrays to detail the glonal perturbations in gene expression in the absence of PSMA, in order to identify disease-specific driving pathways that may lead to new therapies for cancer."
Overall design from the GEO: "LNCaP-Ctrl (PSMA +ve) cells grown on Petri dishes and in complete media where compared with LNCaP cells lacking PSMA (Platinum Select retroviral shRNA-mir platform DU53991)"
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Access via GEO
CEL files of expression profiling by array
Accession #: GSE104417Access via BioProjectAdditional information about the overall initiative.
Accession #: PRJNA412567 - Access Restrictions
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Free to All
- Access Instructions
- The NCBI Gene Expression Omnibus and BioProject databases provide open access to these files.
- Associated Publications
- Data Type
- Equipment Used
- Software Used
- Dataset Format(s)
- TAR, CEL
- Dataset Size
- 11.2 MB (TAR of CEL)
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