Genomic and Transcriptomic Landscape of Fibrolamellar Hepatocellular Carcinoma
UID: 10705
- Description
- Study Description from dbGaP: "Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare liver tumor primarily affecting adolescents and young adults. Little is known of the molecular pathogenesis. To characterize the disease we performed RNA sequencing and whole genome sequencing on FL-HCC tumors and adjacent normal tissue. The results demonstrate few consistent differences on the chromosomal level and many hundreds of alterations in the expression of RNA transcripts."
Study Design:
Tumor vs. Matched-Normal
Study Type:
Cohort
Total number of consented subjects: 11
Hepatocellular Carcinoma
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Access via dbGaP
Whole Genome and RNA Sequence reads for 29 samples in 11 subjects.
Accession #: phs000709.v1.p1 - Access Restrictions
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Application Required
- Access Instructions
- Full access to this dataset in dbGaP requires authorization through an Authorized Access Portal which can be requested for either 'data download' or 'view only'. Individual level data download requires a project request. With dbGaP DataBrowser approval, users may view the collection compilation of individual-level data from general research use. Upon approval data can be downloaded.
A full list of and information about the SRA runs, BioSamples, and experiments is publicly viewable by going to the 'Molecular Datasets' tab and clicking on 'RunSelector' at the bottom of the page. This will take you to the NCBI SRA Run Selector platform, however view and download of the datasets themselves still requires authorization through dbGaP. - Associated Publications
- Data Type
- Equipment Used
- Software Used
- Dataset Format(s)
- SRA
- Dataset Size
- 97.68 Gb
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