Cryo-EM structure of the Caspase-1-CARD:ASC-CARD octamer
UID: 10791
- Description
- This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the cryo-EM structure of CARD8-CARD filament. The main summary display for this entry includes information on the experimental method, validation and macromolecules in the deposit, as well as entry history and funding information. Data is provided for download as FASTA sequence format, the Protein Data Bases own PDB format, crystallographic information file (.cif), XML, the EM map, as well as the full validation file in either PDF or XML formats. Additionally, the PDB provides embedded visualization software to display a 3D view of the protein: PDB's Mol* viewer, NGL viewer, and JSmol. PDB provides protein family and gene product annotations, additional details about the experiment parameters, a Protein Feature Viewer (in the Sequence tab) which displays all available features and alignments of known polymer instances, and a genome view which provides graphical summaries of the correspondences between PDB Entity sequences and genomes.
The associated EMPIAR Image Set, linked here, includes the 2D tiff images use to develop the 3D modeling.
-
Access via PDB
Research Collaboratory for Structural Bioinformatics Protein Data Base
Accession #: 7KEUAccess via EMPIARMulti-frame micrographs for the ASC-CASP1 CARD octamer
Accession #: EMPIAR-10566 - Access Restrictions
-
Free to All
- Access Instructions
- The RCSB Protein Data Base provides access to 3D structure data for large biological molecules (proteins, DNA, and RNA). Sequence, protein structure, EM, and other data can be downloaded in formats specific to the data they contain.
EMPIAR, the Electron Microscopy Public Image Archive, is a public resource for raw electron microscopy images, the raw images used to build a 3D structure. Image sets are available for browsing and download. Accessions are linked to their related PDB and EMDB entries. - DOI
- 10.2210/pdb7KEU/pdb
- Associated Publications
- Data Type
- Equipment Used
- Software Used
- Dataset Format(s)
- PDF, XML, FASTA, PDB, CIF, MAP
- Data Tool(s)
-
Electron Microscopy
- Dataset Size
- 393 KB (FASTA), 108 KB (PDB)
Do you have or know of a dataset that should be added to the catalog? Let us know!