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Hao Wu Lab OSF figures and Pymol/chimera session files

UID: 10792

Author(s): Hollingsworth, Louis R., Xia, Shiyu, Sharif, Humayun, David, Liron, Fontana, Pietro, Li, Yang, Griswold, Andrew*, Bachovchin, Daniel*, Wu, Hao * MSK affiliated

Description
Open Science Framework (OSF) is a repository with tools for data discovery, collection, storage and analysis, as well as study experiment design and publication. The Hao Wu Lab files are organized according to the publication they support. Available files include figures used in publications, PyMOL (.pse) and Chimera (.csx) session files which generate the 3D display of biological molecules and .pdb and .vaf files characterizing marcomolecules. Software to process this data is not immediately accessible from OSF.
Subject(s)
CARD Signaling Adaptor Proteins
Caspase Activation and Recruitment Domain
Inflammasomes
NLR Proteins
Access via OSF

Publicly accessible files supporting and demonstrating the labs research

Access Restrictions
Free to All
Access Instructions
This data is publicly accessible through the Open Science Framework. All files available from the site can be downloaded as a single compressed file as a button from the file browser on the display page. Single files are also accessible for individual, uncompressed download by navigating or searching the file browser.

The files free to access and use. Licensing is Creative Commons (CC-By Attribution 4.0 International)
DOI
10.17605/OSF.IO/X7DV8
Associated Publications
Robert Hollingsworth L, David L, Li Y, et al. Ruan J, Sharif H, Fontana P, Orth-He E, Fu T, Bachovchin D, Wu H. Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. Nature Communications. 2021; 12:189.
Xia S, Hollingsworth LR 4th, Wu H. Mechanism and Regulation of Gasdermin-Mediated Cell Death. Cold Spring Harb Perspect Biol. 2020;12(3):a036400. Published 2020 Mar 2.
Software Used
PyMOL

A molecular visualization system on an open-source foundation

Dataset Format(s)
PDF, Powerpoint Presentation, PDB, PNG, JPG, PSE, CXS, VAF
Dataset Size
6.3 GB
Data Catalog Record Updated
2021-08-03