SPX domain proteins are agents of inositol pyrophosphate toxicosis in fission yeast

Default Boolean Operator: Terms in a search string will be connected by the AND operator, EXAMPLE: searching genomic melanoma will produce the same results as genomic AND melanoma .
AND, OR, NOT: Combine terms in a search with the boolean operators AND (to add specificity), OR (to broaden), or NOT (to eliminate a term). Operators must be capitalized (all other search terms are not case-sensitive).
Wild Card: Add wild card symbols * (open-ended) and ? (single character) to truncate terms. EXAMPLE: searching gen* shows results for 'gene', 'genetic', 'genomic, etc. Searching gene? returns results for 'gene' or 'genes' but not for 'genome'.
Phrase Searching: Enclose search in quotation marks "keyword or search term" to search for an exact phrase. EXAMPLE: "transcription factors" returns results for records where transcription is immediately followed by the word factors .
Diacritics: Words containing diacritics translate those characters to non-diacritic form. EXAMPLE: massague returns results for Massague&#769 .
Filter by: Located on the homepage (left panel), use filters to search for records or narrow the search. From search results page, filters can be removed by clicking on the term at the top of the page.

UID: 10933

Author(s): Garg, Angad*, Schwer, Beate, Shuman, Stewart H.* * MSK affiliated

Description: Summary from GEO:

"This RNA-Seq analysis compares gene expression of spx1∆ mutant contrasting to the WT fission yeast S. pombe."

Overall design from GEO:

"1 test sample and 1 control sample was processed (each sample has 3 replicate experiments). WT samples cultured at the same time and sequenced in the same run were previously deposited in GEO dataset GSE164616."

Subject of Study

Subject(s)

Access via GEO

Accession #: GSE185441

Access via BioProject

Accession #: PRJNA769102

Access via SRA

Accession #: SRP340254
Access Restrictions: Free to All
Access Instructions: The NCBI Gene Expression Omnibus, BioProject, and SRA databases provide open access to these files.
Associated Publications: Schwer B, Garg A, Sanchez A, Bernstein M, Benjamin B, Shuman S. Cleavage-polyadenylation factor Cft1 and SPX domain proteins are agents of inositol pyrophosphate toxicosis in fission yeast. mBio. 2022; 13(1):e03476-21.
Equipment Used: Illumina NovaSeq 6000
Dataset Format(s): Microsoft Excel
Dataset Size: 1.1 MB (XLSX), 333.2 KB (XLSX)

Do you have or know of a dataset that should be added to the catalog? Let us know!