Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis (CHX experiments)

Default Boolean Operator: Terms in a search string will be connected by the AND operator, EXAMPLE: searching genomic melanoma will produce the same results as genomic AND melanoma .
AND, OR, NOT: Combine terms in a search with the boolean operators AND (to add specificity), OR (to broaden), or NOT (to eliminate a term). Operators must be capitalized (all other search terms are not case-sensitive).
Wild Card: Add wild card symbols * (open-ended) and ? (single character) to truncate terms. EXAMPLE: searching gen* shows results for 'gene', 'genetic', 'genomic, etc. Searching gene? returns results for 'gene' or 'genes' but not for 'genome'.
Phrase Searching: Enclose search in quotation marks "keyword or search term" to search for an exact phrase. EXAMPLE: "transcription factors" returns results for records where transcription is immediately followed by the word factors .
Diacritics: Words containing diacritics translate those characters to non-diacritic form. EXAMPLE: massague returns results for Massague&#769 .
Filter by: Located on the homepage (left panel), use filters to search for records or narrow the search. From search results page, filters can be removed by clicking on the term at the top of the page.

UID: 10936

Author(s): Garg, Angad*, Shuman, Stewart H.*, Schwer, Beate * MSK affiliated

Description: Summary from GEO:

"This RNA-Seq analysis compares gene expression of fission yeast cells (Schizosaccharomyces pombe) at various times after phosphate starvation (2, 4, and 8 HR) either with 100 µg/ml cycloheximide or without drug contrasting to the cells grown in phosphate replete conditions (0HR) in the absence of the drug."

Overall design from GEO:

"6 test samples (cycloheximide or no drug treated phosphate starved cells) were analyzed; 1 control sample (no drug, phosphate replete cells); 3 biological replicate for each sample were processed."

Subject of Study

Subject(s)

Access via GEO

Accession #: GSE217952

Access via BioProject

Accession #: PRJNA901456
Access Restrictions: Free to All
Access Instructions: The NCBI Gene Expression Omnibus and BioProject databases provide open access to these files.
Associated Publications: Garg A, Sanchez A, Miele M, Schwer B, Shuman S. Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis. Nucleic Acids Research. 2023; 51(7):3094-3115.
Equipment Used: Illumina NovaSeq 6000
Dataset Format(s): Microsoft Excel
Dataset Size: 938.3 KB, 922.7 KB, 937.4 KB, 933.6 KB, 935.9 KB, 933.7 KB, 764.7 KB

Do you have or know of a dataset that should be added to the catalog? Let us know!