Cell state diversity promotes metastasis through heterotypic cluster formation in melanoma [RNA-Seq]

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UID: 10977

Author(s): Rao, Anjali, Campbell, Nathaniel*, Xavier, Joao B.*, White, Richard Mark*, Yanai, Itai * MSK affiliated

Description: Summary from GEO:

"We report single-cell gene expression profiling of the zebrafish melanoma cell lines ZMEL1-PRO and ZMEL1-INV under multiple in vitro and in vivo (zebrafish transplant) conditions."

Overall design from GEO:

"Single-cell RNA-seq of ZMEL1-PRO and ZMEL1-INV cells in one of four conditions: 1) in vitro individual culture; 2) in vitro co-culture; 3) in vivo primary tumors; and 4) in vivo metastases."

Subject of Study

Subject(s)

OncoTree Cancer Type(s)

Melanoma

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