Genetic interactions and transcriptomics implicate fission yeast CTD prolyl isomerase Pin1 as an agent of RNA 3' processing and transcription termination that functions via its effects on CTD phosphatase Ssu72

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UID: 11002

Author(s): Garg, Angad*, Sanchez, Ana M.*, Schwer, Beate, Shuman, Stewart H.* * MSK affiliated

Description: Summary from GEO:

"This RNA-Seq analysis compares gene expression of the peptidyl-prolyl isomerase Pin1 mutant pin1∆ contrasting to the WT in the fission yeast S. pombe."

Overall design from GEO:

"1 test sample (mutant) was analyzed; 1 WT control sample, sequenced at the same time, was previously deposited in GEO dataset GSE131237 (each sample has 3 replicate experiments)."

Subject of Study

Subject(s)

Access via GEO

Accession #: GSE144092

Access via BioProject

Accession #: PRJNA602734

Access via SRA

Accession #: SRP244077
Access Restrictions: Free to All
Access Instructions: The NCBI Gene Expression Omnibus, BioProject, and SRA databases provide open access to these files.
Associated Publications: Sanchez A, Garg A, Shuman S, Schwer B. Genetic interactions and transcriptomics implicate fission yeast CTD prolyl isomerase Pin1 as an agent of RNA 3' processing and transcription termination that functions via its effects on CTD phosphatase Ssu72. Nucleic Acids Research. 2020; 48(9):4811-4826.
Equipment Used: Illumina HiSeq 4000
High throughput gene sequencing system
Dataset Format(s): TXT
Dataset Size: 444.7 KB

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