Fission yeast poly(A) polymerase active site mutation Y86D alleviates the rad24 Δ asp1-H397A synthetic growth defect and up-regulates mRNAs targeted by MTREC and Mmi1

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UID: 11008

Author(s): Garg, Angad*, Shuman, Stewart H.*, Schwer, Beate * MSK affiliated

Description: Summary from GEO:

"This RNA-Seq analysis compares gene expression of the pla1-Y86D mutant contrasting to the isogenic wild-type fission yeast (Schizosaccharomyces pombe)."

Overall design from GEO:

"1 test samples and 1 control sample was processed (each sample has 3 replicate experiments)."

Subject of Study

Subject(s)

Access via GEO

Accession #: GSE221438

Access via BioProject

Accession #: PRJNA914304
Access Restrictions: Free to All
Access Instructions: The NCBI Gene Expression Omnibus and BioProject databases provide open access to these files.
Associated Publications: Garg A, Schwer B, Shuman S. Fission yeast poly(A) polymerase active site mutation Y86D alleviates the rad24Δ asp1-H397A synthetic growth defect and up-regulates mRNAs targeted by MTREC and Mmi1. RNA. 2023; 29(11):1738-1753.
Equipment Used: Illumina NovaSeq 6000
Dataset Format(s): Microsoft Excel
Dataset Size: 1.2 MB (2 XLSX files)

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