Effects of loss of LSD1 activity on small cell lung cancer cell lines via pharmacological inhibition

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UID: 11025

Author(s): Nguyen, Evelyn M.*, Chow, Andrew*, Rudin, Charles M.* * MSK affiliated

Description: Summary from GEO:

"To investigate the effects of loss of LSD1 (KDM1A) on differential gene expression, we treated two cell lines of small cell lung cancer with 1uM LSD1 inhibitor ORY-1001 or vehicle control for 10 days. We then performed gene expression profiling analysis on treated and control cells for each of the two cell lines."

Overall design from GEO:

"Comparative gene expression profiling for SCLC cell lines with or without treatment with LSD1 inhibitor."

Subject of Study

Subject(s)

OncoTree Cancer Type(s)

Small Cell Lung Cancer

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