MSK MetTropism (MSK, Cell 2021)
UID: 11065
- Description
- Description from cBioPortal:
"MSK-MET (Memorial Sloan Kettering - Metastatic Events and Tropisms) is an integrated pan-cancer cohort of tumor genomic and clinical outcome data from 25,000 patients. We analyzed this dataset to identify associations between tumor genomic alterations and patterns of metastatic dissemination across 50 tumor types. We found that chromosomal instability is strongly correlated with metastatic burden in some tumor types, including prostate adenocarcinoma, lung adenocarcinoma and HR+/HER2+ breast ductal carcinoma, but not in others, such as colorectal MSS, pancreatic adenocarcinoma and high-grade serous ovarian cancer. We also identified specific somatic alterations associated with increased metastatic burden and specific routes of metastatic spread. Our data offer a unique resource for the investigation of the biologic basis for metastatic spread and highlight the crucial role of chromosomal instability in cancer progression."
Lung Adenocarcinoma In Situ
Prostate Adenocarcinoma
- Access Restrictions
-
Free to All
- Access Instructions
- This cBioPortal for Cancer Genomics dataset is publicly available for viewing online as tables, graphs, and/or charts. The data is also available for download in its entirety as a tarball or as individual TSV (tab separated value) files. Some features are only available by logging in with a Google or Microsoft account. These features include storing your virtual studies and groups which allows you to access your studies and groups from any computer, and to allow cBioPortal to remember your study view charts preferences for each study (i.e. order of the charts, type of charts and visibility). Login is optional and not required to access any of the other features of cBioPortal.
- Associated Publications
- Equipment Used
- Software Used
- Dataset Format(s)
- TSV
- Dataset Size
- 8.7 MB
Do you have or know of a dataset that should be added to the catalog? Let us know!