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Supplementary Tables from Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma

UID: 11073

Author(s): Mondello, Patrizia*, Tadros, Saber, Teater, Matt, Fontan, Lorena, Chang, Aaron Y.*, Jain, Neeraj, Yang, Haopeng, Singh, Shailbala, Ying, Hsia-Yuan, Chu, Chi-Shuen, Ma, Man Chun John, Toska, Eneda*, Alig, Stefan, Durant, Matthew, de Stanchina, Elisa*, Ghosh, Sreejoyee, Mottok, Anja, Nastoupil, Loretta, Neelapu, Sattva S., Weigert, Oliver, Inghirami, Giorgio, Baselga, Jose*, Younes, Anas*, Yee, Cassian, Dogan, Ahmet*, Scheinberg, David A.*, Roeder, Robert G., Melnick, Ari M., Green, Michael R. * MSK affiliated

Description
13 supplementary tables supporting "Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma." The contents of the tables are as follows:

Table S1: Differential H3K27Ac in CREBBP-WT vs CREBBP-R1446C
Table S2: Differentially expressed genes in CREBBP-WT vs CREBBP-R1446C
Table S3: Hypergeometric gene set enrichment analysis of differential H3K27Ac between WT and R1446C CRISPR cells
Table S4: Hypergeometric gene set enrichment analysis of differentially expressed genes between WT and R1446C CRISPR cells
Table S5: Comparison of clinical factors between CREBBP LOP and KAT mutation groups
Table S6: Changes in gene expression in R1446C cells induced by BRD3308
Table S7: Hypergeometric gene set enrichment analysis of differential gene expression induced by BRD3308 in R1446C cells
Table S8: Hypergeometric gene set enrichment analysis of H3K27Ac changes induced by BRD3308 in R1446C cells
Table S9: Changes in gene expression in WT cells induced by BRD3308
Table S10: Hypergeometric gene set enrichment analysis of differential gene expression induced by BRD3308 in WT cells
Table S11: Differentially expressed genes in BRD3308 vs vehicle treated DLBCL cell lines
Table S12: Hypergeometric gene set enrichment analysis of differentially expressed genes induced by BRD3308 in DLBCL cell lines
Table S13: Primer sequences
Subject of Study
Homo sapiens
Subject(s)
Gene Expression
Histone Acetyltransferases
Lymphoma, B-Cell
Mutation/genetics