ANKRD31 protein interactions

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UID: 11082

Author(s): Li, Zhuoning*, Keeney, Scott * MSK affiliated

Description: Description from PRIDE:

"Sex chromosomes in males of most mammalian species share only a small homologous segment, the pseudoautosomal region (PAR), wherein double-strand break (DSB) formation must occur for correct meiotic segregation. We find that multiple DSB-promoting factors hyperaccumulate in the PAR, including the ankyrin-repeat domain-containing protein ANKRD31. We used immunoprecipitation and mass spectrometry from extracts of juvenile mouse testes to identify potential ANKRD31-interacting proteins."

Subject of Study

Subject(s)

Access via PRIDE

Accession #: PXD017191
Access Restrictions: Free to All
Access Instructions: All public datasets available in PRIDE Archive in the repository can be accessed via the website by FTP link, Web Service (for programmatic access), and the PRIDE Inspector stand-alone tool.
Associated Publications: Acquaviva L, Boekhout M, Karasu M, Brick K, Pratto F, Li T, van Overbeek M, Kauppi L, Camerini-Otero R, Jasin M, Keeney S. Ensuring meiotic DNA break formation in the mouse pseudoautosomal region. Nature. 2020; 582(7812):426-431.
Equipment Used: Q Exactive
Mass Spectrometer
Software Used: MaxQuant
A quantitative proteomics software package designed for analyzing large mass-spectrometric data sets. It is specifically aimed at high-resolution MS data.
Dataset Format(s): RAW, TXT
Dataset Size: 6 GB

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