Human proteome derivatized with iodoacetamide and acrylamide

Default Boolean Operator: Terms in a search string will be connected by the AND operator, EXAMPLE: searching genomic melanoma will produce the same results as genomic AND melanoma .
AND, OR, NOT: Combine terms in a search with the boolean operators AND (to add specificity), OR (to broaden), or NOT (to eliminate a term). Operators must be capitalized (all other search terms are not case-sensitive).
Wild Card: Add wild card symbols * (open-ended) and ? (single character) to truncate terms. EXAMPLE: searching gen* shows results for 'gene', 'genetic', 'genomic, etc. Searching gene? returns results for 'gene' or 'genes' but not for 'genome'.
Phrase Searching: Enclose search in quotation marks "keyword or search term" to search for an exact phrase. EXAMPLE: "transcription factors" returns results for records where transcription is immediately followed by the word factors .
Diacritics: Words containing diacritics translate those characters to non-diacritic form. EXAMPLE: massague returns results for Massague&#769 .
Filter by: Located on the homepage (left panel), use filters to search for records or narrow the search. From search results page, filters can be removed by clicking on the term at the top of the page.

UID: 11102

Author(s): Kentsis, Alex* * MSK affiliated

Description: This dataset was generated to parametrize and benchmark software for unbiased discovery of post-translationally modified peptides.

Subject of Study

Subject(s)

Access via PRIDE

Accession #: PXD019793
Access Restrictions: Free to All
Access Instructions: All public datasets available in PRIDE Archive in the repository can be accessed via the website by FTP link, Web Service (for programmatic access), and the PRIDE Inspector stand-alone tool.
Associated Publications: Cifani P, Li Z, Luo D, Grivainis M, Intlekofer A, Fenyö D, Kentsis A. Discovery of protein modifications using differential tandem mass spectrometry proteomics. Journal of Proteome Research. 2021; 20(4):1835-1848.
Equipment Used: Orbitrap Fusion Lumos
Software Used: Byonic
Full MS/MS search engine for comprehensive peptide and protein identification

MSFragger
an ultrafast database search tool for peptide identification in mass spectrometry-based proteomics

SAMPEI
open-source algorithm designed for the discovery of functional protein and peptide signaling modifications

X! Tandem
software that can match tandem mass spectra with peptide sequences, in a process that has come to be known as protein identification.
Dataset Format(s): TSV, RAW
Dataset Size: 1.8 GB

Do you have or know of a dataset that should be added to the catalog? Let us know!