HEK293T cell translatome analysis upon Torin1 treatment or single amino acid withdrawal. Related to Supplementary Table 2 from An et al (2020)

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UID: 11128

Author(s): Ordureau, Alban Simon Georges*, Harper, Wade J. * MSK affiliated

Description: HEK293T subject to Torin1 treatment or amino acid withdraw dataset and translatome analysis was determined using Azidohomoalanine (AHA) incorportation, Biotin-click, and streptavidin enrichment. TMT 10plex labelling was used. Three genotypes, WT (24 fractions), ATG7 KO (HA-9-53-1 single shot), RB1CC1 KO (HA-9-53-2 single shot).

Subject of Study

Subject(s)

Access via PRIDE

Accession #: PXD018252
Access Restrictions: Free to All
Access Instructions: All public datasets available in PRIDE Archive in the repository can be accessed via the website by FTP link, Web Service (for programmatic access), and the PRIDE Inspector stand-alone tool.
Associated Publications: An H, Ordureau A, Körner M, Paulo JA, Harper JW. Systematic quantitative analysis of ribosome inventory during nutrient stress. Nature. 2020 Jul;583(7815):303-309. Epub 2020 Jul 1. PMID: 32612236; PMCID: PMC7351614.
Equipment Used: Orbitrap Fusion Lumos
Dataset Format(s): RAW
Dataset Size: 26 GB

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