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Description
Summary from GEO:

"Single cell TCR/RNA sequencing was performed on sorted PSlow and PShigh CD8 T cells from five MC38-LG bearing mice that had been treated with anti-Tim-4 and anti-PD-1. Cells from the individual mice were hashtagged to allow subsequent deconvolution."
Subject of Study
Mus musculus
Subject(s)
CD8-Positive T-Lymphocytes
RNA-Seq
Single-Cell Analysis
Tumor-Associated Macrophages
Access via GEO


Accession #: GSE174241

Access via BioProject


Accession #: PRJNA728907

Access via SRA


Accession #: SRP319362

Access Restrictions
Free to All
Access Instructions
The NCBI Gene Expression Omnibus, BioProject, and SRA databases provide open access to these files.
Associated Publications
Chow A, Schad S, Green M, et al. Tim-4(+) cavity-resident macrophages impair anti-tumor CD8(+) T cell immunity. Cancer Cell. 2021; 39(7):973-988.e9.
Equipment Used
Illumina NextSeq 500
Illumina NovaSeq 6000
Dataset Format(s)
CSV, MTX, TXT
Dataset Size
358 MB
Data Catalog Record Updated
2024-02-02