RNA-seq of tumor cells sorted from YAPS127A and BrafV600E/YAPS127A mouse thyroid tumors

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UID: 11149

Author(s): Garcia-Rendueles, Maria E. R.*, Fagin, James A.*, Knauf, Jeffrey A*, Saqcena, Mahesh* * MSK affiliated

Description: Summary from GEO:

"We performed high-throughput RNA sequencing of tumor cells sorted from YAPS127A and BrafV600E/YAPS127A to investigate YAP dependency and driver cooperativity in thyroid tumor progression."

Overall design from GEO:

"mRNA profiles of thyroid cancer cells from YAPS127A and BrafV600E/YAPS127A mice."

Subject of Study

Subject(s)

Access via GEO

Accession #: GSE198381

Access via BioProject

Accession #: PRJNA814731
Access Restrictions: Free to All
Access Instructions: The NCBI Gene Expression Omnibus and BioProject databases provide open access to these files.
Associated Publications: Garcia-Rendueles M, Krishnamoorthy G, Saqcena M, Acuña-Ruiz A, Revilla G, de Stanchina E, Knauf J, Lester R, Xu B, Ghossein R, Fagin J. Yap governs a lineage-specific neuregulin1 pathway-driven adaptive resistance to RAF kinase inhibitors. Molecular Cancer. 2022; 21:213.
Equipment Used: Illumina HiSeq 4000
High throughput gene sequencing system
Dataset Format(s): TXT
Dataset Size: 671.6 KB

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