mmsig

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UID: 11264

Author(s): Maura, Francesco*, Rustad, Even H.*, Angelopoulos, Nicos, Ziccheddu, Bachisio * MSK affiliated

Description: Description from GitHub:

"The goal of mmsig is to provide a flexible and easily interpretable mutational signature analysis tool. mmsig was developed for hematological malignancies, but can be extended to any cancer with a well-known mutational signature landscape.

mmsig is based on an expectation maximization algorithm for mutational signature fitting and applies cosine similarities for dynamic error suppression as well as bootstrapping-based confidence intervals and assessment of transcriptional strand bias."

Subject(s)

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