RNA-seq of MUTZ3 cells in experiments to investigate EVI1 regulation

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UID: 11322

Author(s): Delwel, Ruud

Description: Description from EMBL-EBI:

"We investigated whether GATA2 enhancer-driven transcription of EVI1 in inv(3)/t(3;3) is reversible in leukemia cells. In primary inv(3)/t(3;3) AML, immature CD34+CD15- cells can be discriminated from more mature CD34-CD15- and CD34-CD15+ cells. Besides, we also investigated the effect of deleting a MYB binding site on these cells using CRISPR/Cas9."

Detailed sample and protocol information via EMBL-EBI.

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