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ChIP-seq of primary AML patients with t(3;3)/inv(3)

UID: 11328

Publisher(s): European Genome-phenome Archive

Description
Description from EGA:

"ChIP-seq was conducted in blasts from patients with t(3;3) AML to assess differences of the GATA2 super-enhancer between the translocated allele and the non-translocated allele. The dataset includes 2x H3K27ac ChIP-seq and 1x MYB ChIP-seq.

ChIP samples were processed according to the Illumina TruSeq ChIP Sample Preparation Protocol (Illumina) or Diagenode Library V3 preparation protocol (Diagenode) and either sequenced single-end (1x 50 bp) on the HiSeq 2500 platform (Illumina) or paired-end (2x100 bp) on the Novaseq 6000 platform (Illumina). Briefly, reads were aligned to the human reference genome build hg19 with bowtie for single-end runs and bowtie2 for paired-end runs."
Subject of Study
Subject(s)
OncoTree Cancer Type(s)
Acute Myeloid Leukemia
Access via EGA


Accession #: EGAD00001006821

Access Restrictions
Application Required
Access Instructions
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Associated Publications
Equipment Used
Illumina HiSeq 2500
Illumina NovaSeq 6000
Dataset Format(s)
BAI
Dataset Size
7.7 GB
Data Catalog Record Updated
2024-08-09