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Growth factor-mediated coupling between lineage size and cell fate choice underlies robustness of mammalian development: Code for phase-plane analysis and modeling

UID: 11392

Description
Description from GitHub:

"This repository contains the code to reproduce the modeling figures of the paper by Saiz et al, published in eLife 2020;9:e56079 (doi: 10.7554/eLife.56079) and posted in bioRxiv (preprint 2019.12.27.889006). It includes the following:

fig2b.ipynb: self-contained Jupyter notebook to generate the phase portrait shown in Figure 2b.
fig2c.ipynb: Jupyter notebook to generate the lineage dynamics plot shown in Figure 2c. This notebook compiles and runs the C program embryo_v1.c, and plots the correspoding results. It requires the C compiler cc and the utility make, which are available by default in Linux, or by installing the Xcode development environment in Mac OS X.
fig2e.ipynb: Jupyter notebook to generate the lineage dynamics plots shown in Figure 2e, using again the C program embryo_v1.c.
fig3.ipynb: Jupyter notebook to generate the ESC addition plots shown in Figure 3, using in this case the C program embryo_v2.c.
fig4.ipynb: Jupyter notebook to generate the ablation plots shown in Figure 4, using again the C program embryo_v1.c."
Subject(s)
Access Restrictions
Free to All
Access Instructions
Available through GitHub via a GNU General Public License
Associated Publications
Software Used
C
Dataset Format(s)
PDF, MD, IPYNB, C
Dataset Size
857 KB
Data Catalog Record Updated
2024-10-03