mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase: MassIVE MSV000095724

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UID: 11477

Author(s): Ordureau, Alban Simon Georges* * MSK affiliated

Description: Description from MassIVE:

"Supporting MS data for paper (DOI:10.1016/j.celrep.2024.115179) by Pham, B. et al., titled "mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase". Related to Table S1 - HEK293 - degradomics (HA-2-165 | Unimod:35; 2016; 4 | 126 - Neg Ctrl (WT cells -AHA); 127n - MAEA-WT - UT_0h replicate 1; 127c - MAEA-WT - UT_0h replicate 2; 128n - MAEA-WT - UT_0h replicate 3; 128c - MAEA-WT - UT_10h replicate 1; 129n - MAEA-WT -UT_10h replicate 2; 129c - MAEA-WT - Tor1_10h replicate 1; 130n - MAEA-WT - Tor1_10h replicate 2; 130c - MAEA-WT - Tor1_10h replicate 3; 131n - MAEA[Y394A] - UT_0h replicate 1; 131c - MAEA[Y394A] - UT_0h replicate 2; 132n - MAEA[Y394A] - UT_0h replicate 3; 132c - MAEA[Y394A] - UT_10h replicate 1; 133n - MAEA[Y394A] - UT_10h replicate 2; 133c - MAEA[Y394A] - UT_01h replicate 3; 134n - MAEA[Y394A] - Tor1_10h replicate 1; 134c - MAEA[Y394A] - Tor1_10h replicate 2; 135n - MAEA[Y394A] - Tor1_10h replicate 3)"

Subject of Study

Subject(s)

Access via MassIVE

Accession #: MSV000095724
Access Restrictions: Free to All
Access Instructions: Public access dataset available under a CC0 1.0 Universal (CC0 1.0) license
DOI: 10.25345/C5DF6KF4S
Associated Publications: Pham B, Yi S, Ordureau A, An H. mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase. Cell Reports. 2025; 44(1):115179.
Equipment Used: Orbitrap Eclipse
Mass spectrometer
Dataset Format(s): MZXML
Dataset Size: 15.07 GB