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  • Adenoid Cystic Carcinoma Project (J Clin Invest 2019)

    Description

    Multi-Institute Cohort of 1045 Adenoid Cystic Carcinoma patients. This dataset contains summary data visualizations and clinical data from a broad sampling of 1045 adenoid cystic carcinomas. The data was gathered in support of an article in the Journal of Clinical Investigation. The clinical data includes mutation count, information about mutational analysis, patient demographics, survival status,...

    Subject
    Carcinoma, Adenoid Cystic
    Access Rights
    Free to All
  • The mutational characterization of adenoid cystic carcinoma

    Authors
    Chan, Timothy A.
    Description

    Description from dbGaP: "Adenoid cystic carcinoma (ACC) typically emanate from the major and minor salivary glands of the head and neck. ACCs have high rates of perineural invasion, locoregional recurrence, and distant metastasis. Here we report sequencing of 60 tumor/normal pairs and find substantial mutational diversity. On pathway analysis, a significant percentage of mutations involved chromatin...

    Subject
    Carcinoma, Adenoid Cystic
    DNA Damage
    Mutation
    Salivary Gland Neoplasms
    Whole Genome Sequencing
    Access Rights
    Application Required