This dataset contains summary data visualizations and clinical data from a broad sampling of tropomyosin receptor kinase (TRK) fusion tumors. The data was gathered utilizing the MSK-IMPACT targeted sequencing test. The clinical data includes tumor type (based on the opensource OncoTree ontology developed at MSK), information about mutated genes, patient demographics, and modality. The data set also...

This dataset contains the summary data visualizations and clinical data of Poorly-Differentiated and Anaplastic Thyroid Cancers with targeted sequencing of 341 cancer genes from 117 patient-derived PDTCs and ATCs. Clinical data includes: Mutation Count, Fraction Genome Altered, Diagnosis Age, Overall Survival Status, Metastasis/Primary Sample type, Patient Sex, AJCC Tumor Stage Code, Cytological Phenotype,...

Summary from the GEO: "BACKGROUND. Poorly-differentiated (PDTC) and anaplastic (ATC) thyroid cancers are rare and frequently lethal tumors, which so far have not been subjected to comprehensive genetic characterization. METHODS. We performed next generation sequencing of 341 cancer genes in 117 PDTCs and ATCs, and a transcriptomic analysis of a representative subset of 37 tumors. Results were analyzed...