The Acquisition of Molecular Drivers in Pediatric Therapy-Related Myeloid Neoplasms

Description

Summary from the European Genome-Phenome Archive: "Pediatric therapy-related myeloid neoplasms (tMN) occur in children after exposure to cytotoxic therapy and have a dismal prognosis1-4. The somatic and germline genomic alterations that drive these myeloid neoplasms in children and how they arise have yet to be comprehensively described. We use whole exome, whole genome, and/or RNA sequencing to...

Subject

Leukemia, Myeloid

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