RNA-sequencing of primary mouse hematopoietic stem progenitors

Authors

Elias, Harold K.

Spevak, Christina C.

Park, Christopher Y.

Description

Summary from GEO: "Mechanisms of translational regulation are poorly understood in somatic stem cells. We used polysome profiling, RNA-sequencing, and proteomic approaches to examine translational regulation in hematopoietic stem cell (HSC)-enriched (LSK; Lin-Sca-1+c-Kit+) cells and committed myeloid progenitors (MP). Our studies show that polysomal RNA expression changes more robustly predict changes...

Subject

Adult Stem Cells

Hematopoietic Stem Cells

Myeloid Progenitor Cells

Proteomics

RNA-Seq

Access Rights

Free to All