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  • Data from: Alternative splicing substantially diversifies the transcriptome during early photomorphogenesis and correlates with the energy availability in Arabidopsis

    Authors
    Hartmann, Lisa
    Drewe-Boß, Philipp
    Wießner, Theresa
    Wagner, Gabriele
    8 more author(s)...
    Description

    Summary from Dryad: "Abstract: Plants use light as source of energy and information to detect diurnal rhythms and seasonal changes. Sensing changing light conditions is critical to adjust plant metabolism and to initiate developmental transitions. Here we analyzed transcriptome-wide alterations in gene expression and alternative splicing (AS) of etiolated seedlings undergoing photomorphogenesis...

    Subject
    Alternative splicing
    Arabidopsis
    Gene Expression Regulation, Plant
    Signal Transduction
    Transcriptome
    Access Rights
    Free to All
  • Data from: Splicing factor SF3B1K700E mutant dysregulates erythroid differentiation via aberrant alternative splicing of transcription factor TAL1

    Authors
    Jin, Shuiling
    Su, Hairui
    Tran, Ngoc-Tung
    Song, Jing
    6 more author(s)...
    Description

    Summary from Dryad: "Abstract: More than 60% of myeloid dysplasia syndrome (MDS) contains mutations in genes encoding for splicing factors such as SF3B1, U2AF, SRSF2 and ZRSR2. Mutations in SF3B1 are associated with 80% cases of refractory anemia with ring sideroblast (RARS), a subtype of MDS. SF3B1K700E is the most frequently mutated site among mutations on SF3B1. Yet the molecular mechanisms on...

    Subject
    Alternative splicing
    K562 Cells
    Myelodysplastic Syndromes
    Transcription Factors
    Access Rights
    Free to All