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A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_ChIPseq]
- Authors
- Ludwig, Leif S.Lareau, Caleb A.
- Description
Summary from GEO: "Master regulators, such as the hematopoietic transcription factor GATA1, have numerous roles in lineage commitment and differentiation. While human GATA1 mutations result in several blood diseases, all characterized mutations act relatively early to impair hematopoietic differentiation. Here, we describe a distinct form of hemolytic anemia involving impaired terminal erythropoiesis...
- Subject
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Anemia, Hemolytic, CongenitalChromatin Immunoprecipitation SequencingErythropoiesisGATA1 Transcription Factor
- Access Rights
- Free to All
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A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_RNAseq]
- Authors
- Ludwig, Leif S.Lareau, Caleb A.Sankaran, Vijay
- Description
Summary from GEO: "Master regulators, such as the hematopoietic transcription factor GATA1, have numerous roles in lineage commitment and differentiation. While human GATA1 mutations result in several blood diseases, all characterized mutations act relatively early to impair hematopoietic differentiation. Here, we describe a distinct form of hemolytic anemia involving impaired terminal erythropoiesis...
- Subject
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Anemia, Hemolytic, CongenitalErythropoiesisGATA1 Transcription FactorSequence Analysis, RNA
- Access Rights
- Free to All
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A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_ATACseq]
- Authors
- Ludwig, Leif S.Lareau, Caleb A.
- Description
Summary from GEO: "Master regulators, such as the hematopoietic transcription factor GATA1, have numerous roles in lineage commitment and differentiation. While human GATA1 mutations result in several blood diseases, all characterized mutations act relatively early to impair hematopoietic differentiation. Here, we describe a distinct form of hemolytic anemia involving impaired terminal erythropoiesis...
- Subject
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Anemia, Hemolytic, CongenitalChromatin Immunoprecipitation SequencingErythropoiesisGATA1 Transcription Factor