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  • A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_ChIPseq]

    Authors
    Ludwig, Leif S.
    Lareau, Caleb A.
    Description

    Summary from GEO: "Master regulators, such as the hematopoietic transcription factor GATA1, have numerous roles in lineage commitment and differentiation. While human GATA1 mutations result in several blood diseases, all characterized mutations act relatively early to impair hematopoietic differentiation. Here, we describe a distinct form of hemolytic anemia involving impaired terminal erythropoiesis...

    Subject
    Anemia, Hemolytic, Congenital
    Chromatin Immunoprecipitation Sequencing
    Erythropoiesis
    GATA1 Transcription Factor
    Access Rights
    Free to All
  • A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_RNAseq]

    Authors
    Ludwig, Leif S.
    Lareau, Caleb A.
    Sankaran, Vijay
    Description

    Summary from GEO: "Master regulators, such as the hematopoietic transcription factor GATA1, have numerous roles in lineage commitment and differentiation. While human GATA1 mutations result in several blood diseases, all characterized mutations act relatively early to impair hematopoietic differentiation. Here, we describe a distinct form of hemolytic anemia involving impaired terminal erythropoiesis...

    Subject
    Anemia, Hemolytic, Congenital
    Erythropoiesis
    GATA1 Transcription Factor
    Sequence Analysis, RNA
    Access Rights
    Free to All
  • A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_ATACseq]

    Authors
    Ludwig, Leif S.
    Lareau, Caleb A.
    Description

    Summary from GEO: "Master regulators, such as the hematopoietic transcription factor GATA1, have numerous roles in lineage commitment and differentiation. While human GATA1 mutations result in several blood diseases, all characterized mutations act relatively early to impair hematopoietic differentiation. Here, we describe a distinct form of hemolytic anemia involving impaired terminal erythropoiesis...

    Subject
    Anemia, Hemolytic, Congenital
    Chromatin Immunoprecipitation Sequencing
    Erythropoiesis
    GATA1 Transcription Factor