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Center for Common Disease Genomics [CCDG] - Autoimmune: Inflammatory Bowel Disease (IBD) Exomes and Genomes
- Authors
- Daly, Mark
- Description
Description from dbGaP: "The National Human Genome Research Institute (NHGRI) has funded a collaborative large-scale genome sequencing effort to comprehensively identify rare risk and protective variants contributing to multiple common disease phenotypes. Called the Centers for Common Disease Genomics (CCDG), this initiative will explore a range of diseases with the ultimate goal of: undertaking...
- Subject
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Autoimmune DiseasesCardiovascular DiseasesGenetic Association StudiesInflammatory Bowel DiseasesNervous System DiseasesWhole Genome Sequencing
- Access Rights
- Free to All
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Single-cell RNA-sequencing reveals pervasive but highly cell type-specific genetic ancestry effects on the response to viral infection
- Authors
- Randolph, Haley E.Fiege, Jessica K.Thielen, Beth K.Cobb, M.S.3 more author(s)...
- Description
Description from GEO: "Humans show remarkable variation in susceptibility to infectious diseases as well as chronic inflammatory and autoimmune disorders. This heterogeneity arises partially from variation in the immune response, which is responsible for preventing and controlling infection. To better understand the major factors driving antiviral immune response differences, we used single-cell...
- Subject
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Autoimmune DiseasesInflammationInfluenza A virusInfluenza, HumanLeukocytes, MononuclearSingle-Cell Gene Expression Analysis
- Access Rights
- Free to All