High throughput joint profiling of chromatin accessibility and protein levels in single cells [marrow]

Authors

Mimitou, Eleni P.

Lareau, Caleb A.

Chen, Kelvin Y.

Ludwig, Leif S.

1 more author(s)...

Description

Summary from GEO: "Recent technological advances have enabled massively parallel single-cell Assay for Transposase Accessible Chromatin by sequencing (scATAC-seq) to simultaneously profile the epigenomic landscape in thousands of individual cells. scATAC-seq methods sample genomic DNA accessible to transposases, but have not previously been combined with measurement of protein levels. Here, we present...

Subject

Bone Marrow Examination

Cell Differentiation

Chromatin Immunoprecipitation Sequencing

DNA, Mitochondrial

Hematopoiesis

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