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scRNA-seq analysis of SARS-CoV-2 infected human islets
- Authors
- Chen, ShuibingTang, XumingUhl, Skyler
- Description
Summary from the GEO: "Recent clinical data has suggestedsed a bi-directional relationship between Coronavirus disease 19 (COVID-19) and diabetes. Here, we showdemonstrateed the detection of SARS-CoV-2 in pancreatic endocrine cells in autopsy samples derived fromof COVID-19 patients. Single cell RNA-seq and immunostaining confirmed that multiple types of pancreatic islet cells can be infected byare...
- Subject
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ChemokinesCOVID-19Eukaryotic Initiation Factor-2Islets of Langerhans
- Access Rights
- Free to All
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R Script for the analysis of "SARS-CoV-2 Infection Induces Beta Cell Transdifferentiation "
- Authors
- Zhang, TuoChen, Shuibing
- Description
Summary from GitHub: This repository contains the R scripts necessary to perform the analysis in our paper Tang, Xuming et al. “SARS-CoV-2 Infection Induces Beta Cell Transdifferentiation.” Cell Metabolism, 19 May. 2021, doi:10.1016/j.cmet.2021.05.015, as described in the supplementary methods and main text." Input data: "The single cell RNA-seq data were generated with the 10X Chromium and pre-processed...
- Subject
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ChemokinesCOVID-19Diabetes MellitusEukaryotic Initiation Factor-2
- Access Rights
- Free to All