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Cancer Therapy and Clonal Hematopoiesis (MSK, Clin Cancer Res 2022)
- Description
Clonal hematopoiesis mutations identified in blood samples from patients whose tumor-blood pairs were analyzed using MSK-IMPACT. The clinical data includes mutation count, information about mutated genes, patient demographics, and information about treatment. The data set also includes charts visualizing data summaries and customizable plotting tool.
- Subject
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Clinical TrialDrug TherapyHematopoiesisMutation/genetics
- Access Rights
- Free to All
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CoMMpass IA19: Data from "Gene interaction network analysis in multiple myeloma detects complex immune dysregulation associated with shorter survival"
- Description
The Multiple Myeloma Research Foundation (MMRF) runs a multi-site longitudinal clinical registry study of patients newly diagnosed with MM. This project is called CoMMpass, and collects both clinical and genomic information periodically. Researchers used interim analysis 19 (IA19) for their conclusions in "Gene interaction network analysis in multiple myeloma detects complex immune dysregulation...
- Subject
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Clinical TrialDNA Copy Number VariationsGenomicsMultiple MyelomaRNA-SeqWhole Genome Sequencing
- Access Rights
- Free to all with registration
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Whole exome and whole genome sequencing of pancreatic cancer
- Description
Description from EGA: "These are seven sequencing files form whole exome and whole genome of five tissue samples collected from one pancreatic cancer patient" Dataset is also accessioned as a study, associated with publication "An unusual genomic variant of pancreatic ductal adenocarcinoma with an indolent clinical course," (Kohutek, et. al.), under accession number EGAS00001002192.
- Subject
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Carcinoma, Pancreatic DuctalClinical TrialExome SequencingPancreatic NeoplasmsWhole Genome Sequencing
- Access Rights
- Free to All
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MSK-CHORD (MSK, Nature 2024)
- Description
This dataset contains summary data visualizations and clinical data from targeted sequencing of 25040 tumors from 24950 patients and their matched normals via MSK-IMPACT, along with clinical annotations, some of which are derived from natural language processing (denoted NLP). This data is available under the Creative Commons BY-NC-ND 4.0 license. For commercial use, please contact datarequests@mskcc.org....
- Subject
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Clinical TrialData VisualizationMachine LearningSequence Analysis
- Access Rights
- Free to All
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Breast Cancer (METABRIC, Nature 2012 & Nat Commun 2016)
- Description
This dataset contains summary data visualizations and clinical data from target sequencing analysis of 2509 primary breast tumors from 2,509 patients. The study was conducted to identify putative cancer genes, revealing novel subgroups with distinct clinical outcomes. The results were validated by long-term clinical follow-up. The clinical data includes mutated genes, 3-gene classifier subtypes, and...
- Subject
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Breast NeoplasmsClinical TrialData VisualizationSequence Analysis
- Access Rights
- Free to All