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Table S2 from Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations
- Authors
- Adib, ElioKlonowska, KatarzynaGiannikou, KrinioDo, Khanh T.15 more author(s)...
- Description
Description from Figshare: "Table S2. Demographic and clinical characteristics of 30 cancer patients with mTOR pathway mutations. S2.1. Master table showing a summary of demographic characteristics and clinical outcomes. S2.2. Prior systemic treatment regimens. S2.3. Objective response to everolimus according to RECIST v1.1 criteria. S2.4. Toxicity profile of patients according to CTCAE v4.0."
- Subject
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Clinical Trial, Phase IIEverolimusNeoplasms/drug therapyTOR Serine-Threonine Kinases
- Access Rights
- Free to All
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Table S6 from Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations
- Authors
- Adib, ElioKlonowska, KatarzynaGiannikou, KrinioDo, Khanh T.15 more author(s)...
- Description
Description from Figshare: "Table S6. Copy number alterations (CNAs) in cancer genes identified by whole exome sequencing (WES) and/or initial panel sequencing. Each sheet is a different tumor sample."
- Subject
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Clinical Trial, Phase IIDNA Copy Number VariationsEverolimusHigh-Throughput Nucleotide SequencingNeoplasms/drug therapyTOR Serine-Threonine Kinases
- Access Rights
- Free to All
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Table S5 from Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations
- Authors
- Adib, ElioKlonowska, KatarzynaGiannikou, KrinioDo, Khanh T.15 more author(s)...
- Description
Description from Figshare: "Table S5. Nonsynonymous single nucleotide variants (SNVs) and insertions/deletions (indels) identified by whole exome sequencing (WES) and/or initial panel sequencing. Each sheet is a different tumor sample."
- Subject
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Clinical Trial, Phase IIEverolimusExome SequencingNeoplasms/drug therapyNucleotidesTOR Serine-Threonine Kinases
- Access Rights
- Free to All
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Table S4 from Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations
- Authors
- Adib, ElioKlonowska, KatarzynaGiannikou, KrinioDo, Khanh T.15 more author(s)...
- Description
Description from Figshare; "Table S4. Inactivating mutations in TSC1/TSC2 and activating mutation in MTOR identified in 30 patients in the clinical trial - clonality and biallelic TSC1/TSC2 inactivation status."
- Subject
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Clinical Trial, Phase IIEverolimusNeoplasms/drug therapyTOR Serine-Threonine KinasesTuberous Sclerosis Complex 1 ProteinTuberous Sclerosis Complex 2 Protein
- Access Rights
- Free to All
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Table S1 from Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations
- Authors
- Adib, ElioKlonowska, KatarzynaGiannikou, KrinioDo, Khanh T.15 more author(s)...
- Description
Description from Figshare: "Table S1. Massively Parallel Sequencing (MPS) metrics and cancer sample characteristics."
- Subject
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Clinical Trial, Phase IIEverolimusHigh-Throughput Nucleotide SequencingNeoplasms/drug therapyTOR Serine-Threonine Kinases
- Access Rights
- Free to All
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Table S3 from Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations
- Authors
- Adib, ElioKlonowska, KatarzynaGiannikou, KrinioDo, Khanh T.15 more author(s)...
- Description
Description from Figshare: "Table S3. Toxicities (any level) occurring in at least two patients, grouped by CTCAE v4.0 categories. For patients with more than one adverse event per category, only the highest-grade event was counted."
- Subject
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Clinical Trial, Phase IIDrug-Related Side Effects and Adverse ReactionsEverolimusNeoplasms/drug therapyTOR Serine-Threonine Kinases
- Access Rights
- Free to All
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Nivolumab plus ipilimumab in advanced salivary gland cancer: a phase 2 trial
- Authors
- Burman, BharatJain, SwatiFitzgerald, Conall W.R.Sherman, Eric J.22 more author(s)...
- Description
Description from Zenodo: "This is a de-identified dataset accompanying the Nature Medicine publication titled "Nivolumab plus ipilimumab in advanced salivary gland cancer: a phase 2 trial", by Vos et al. (DOI: https://doi.org/10.1038/s41591-023-02518-x). It contains the clinical features and processed data of 64 patients with salivary gland cancer, treated with nivolumab and ipilimumab immunotherapy....
- Subject
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Clinical Trial, Phase IIImmunotherapyIpilimumabNivolumabSalivary Gland Neoplasms
- Access Rights
- Free to All
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Determinants of Response to Nivolumab plus Ipilimumab in a Phase II Trial of Advanced Salivary Gland Cancer Patients
- Description
Description from BioProject: "Salivary gland cancers (SGCs) are rare, aggressive cancers that lack effective treatments in the metastatic setting. We report the clinical results and immunogenomic correlates of response from a phase II trial evaluating nivolumab (anti-PD1) and ipilimumab (anti-CTLA4) in metastatic SGC patients."
- Subject
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Clinical Trial, Phase IIExome SequencingIpilimumabNivolumabRNA-SeqSalivary Gland Neoplasms
- Access Rights
- Free to All