MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells

Authors

Wei, Qiaozhi

Frenette, Paul S.

Description

Summary from the GEO: "Haematopoietic stem cells (HSCs) tightly regulate their quiescence, proliferation, and differentiation to generate blood cells during the entire lifetime. The mechanisms by which these critical activities are balanced are still unclear. Here, we report that Macrophage-Erythroblast Attacher (MAEA, also known as EMP), a receptor thus far only identified in erythroblastic island1,...

Subject

Cell Adhesion Molecules

Cytoskeletal Proteins

Gene Expression Profiling

Hematopoiesis

Hematopoietic Stem Cells

Leukemia, Myeloid, Acute

Lymphokines

Ubiquitin-Protein Ligases

Access Rights

Free to All