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A multivalent signal-transducing model for the DNMT1-mediated maintenance DNA methylation
- Authors
- Wang, Gang G.Grimm, Sara A.
- Description
Summary from the GEO: "Heterochromatin-specific histone modifications frequently coexist with mammalian DNA methylation to orchestrate a repressive chromatin state. However, it remains elusive how these epigenetic modifications crosstalk. Here, we report that the first bromoadjacent homology (BAH1) domain and the replication foci targeting sequence (RFTS) of maintenance DNA methyltransferase DNMT1...
- Subject
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DNA (Cytosine-5-)-Methyltransferase 1DNA MethylationHeterochromatinHistone CodeHistones
- Access Rights
- Free to All
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Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me2
- Authors
- Ren, WendanSong, Jikui
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes x-ray diffraction data used for modeling the crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me2. The main summary display for this entry includes information on the experimental data, validation, macromolecules, small molecules, version history and funding identification. Data...
- Subject
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DNA (Cytosine-5-)-Methyltransferase 1HistonesMethyltransferasesRepressor Proteins
- Access Rights
- Free to All
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Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me3
- Authors
- Ren, WendanSong, Jikui
- Description
This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes x-ray diffraction data used for modeling the crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me3. The main summary display for this entry includes information on the experimental data, validation, macromolecules, small molecules, version history and funding identification. Data...
- Subject
-
DNA (Cytosine-5-)-Methyltransferase 1HistonesMethyltransferasesRepressor Proteins
- Access Rights
- Free to All