Replication-coupled nucleosome assembly and positioning by ATP-dependent chromatin remodeling enzymes

Authors

Yadav, Tejas

Whitehouse, Iestyn

Description

Summary from GEO: "We have previously shown that Okazaki fragments in Saccharomyces cerevisiae are sized according to the chromatin repeat. Here we demonstrate that nucleosome positioning is rapidly established on newly synthesized DNA. Using deep sequencing, we demonstrate that ATP-dependent chromatin remodeling enzymes, Isw1 and Chd1, collaborate with histone chaperones, such as CAF-1 and Rtt106,...

Subject

Chromatin

DNA Ligase ATP

DNA Replication

High-Throughput Nucleotide Sequencing

Nucleosomes

Access Rights

Free to All