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Spatiotemporal coordination at the maternal-fetal interface promotes trophoblast invasion and vascular remodeling in the first half of human pregnancy
- Authors
- Angelo, MichaelGreenbaum, ShirleyVan Valen, DavidJaswa, Eleni G.9 more author(s)...
- Description
Description from HuBMAP: "Beginning in the first trimester, fetally derived extravillous trophoblasts (EVTs) invade the uterus and remodel its spiral arteries, transforming them into large, dilated blood vessels left with a thin, discontinuous smooth muscle layer and partially lined with EVTs. Several mechanisms have been proposed to explain how EVTs coordinate with the maternal decidua to promote...
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ArteriesExtravillous TrophoblastsMass spectrometryMaternal-Fetal ExchangePlacentaVolume Electron Microscopy
- Access Rights
- Free to all with registration
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A spatially resolved timeline of the human maternal-fetal interface (tissue block images)
- Authors
- Soon, Erin
- Description
Description from Dryad: "Beginning in the first trimester, fetally-derived extravillous trophoblasts (EVTs) invade the uterus and remodel its spiral arteries, transforming them into large, dilated blood vessels. Several mechanisms have been proposed to explain how EVTs coordinate with the maternal decidua to promote a tissue microenvironment conducive to spiral artery remodeling (SAR). However,...
- Subject
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Extravillous TrophoblastsMaternal-Fetal ExchangeMultiomics
- Access Rights
- Free to All
