Single-cell eQTL mapping identifies cell type specific genetic control of autoimmune disease [Genotype_data]

Authors

Yazar, Seyhan

Powell, Joseph E.

Hewitt, Alex W.

Description

Summary from GEO: "The human immune system displays remarkable variation between individuals, leading to differences in susceptibility to autoimmune disease. We present single cell RNA sequence data from 1,267,768 peripheral blood mononuclear cells from 982 healthy human subjects. For 14 cell types, we identified 26,597 independent cis-expression quantitative trait loci (eQTLs) and 990 trans-eQTL,...

Subject

Genotype

Leukocytes, Mononuclear

Mendelian Randomization Analysis

RNA, Messenger

Single-Cell Gene Expression Analysis

Access Rights

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