Description from dbGaP: "These clinical specimens represent solid tumors and matched blood controls that were collected as part of patients' routine care at Memorial Sloan Kettering Cancer Center. They were sequenced on the targeted platform MSK-IMPACT. Here, we performed germline variant calling on the normal blood specimens and assessed their zygosity in the concomitant tumor specimens for comprehensive...

Description from GitHub: "Tempo is a CMO Computational Sciences (CCS) research pipeline processing WES & WGS tumor-normal pairs using the Nextflow framework. Currently the pipeline is composed of alignment and QC, and detection of both somatic alterations and germline variants. Users can begin with inputs of either paired-end FASTQs or BAMs, and process these via the command line. For further details...