Search Tips
of 1 Next >
Results Found: 2

  • Foxp3 exploits a preexistent enhancer landscape for regulatory T cell lineage specification [ChIP-Seq]

    Authors
    Samstein, Robert M.
    Arvey, Aaron
    Rudensky, Alexander Y.
    Description

    Summary from GEO: "Regulatory T (Treg) cells, whose identity and function are defined by the transcription factor Foxp3, are indispensable for immune homeostasis. It is unclear whether Foxp3 exerts its Treg lineage specification function through active modification of the chromatin landscape and establishment of new enhancers or by exploiting a pre-existing enhancer landscape. Analysis of the chromatin...

    Subject
    Chromatin Immunoprecipitation Sequencing
    Forkhead Transcription Factors
    Homeostasis/immunology
    T-Lymphocytes, Regulatory
    Access Rights
    Free to All

  • Foxp3 exploits a preexistent enhancer landscape for regulatory T cell lineage specification [Expression]

    Authors
    Samstein, Robert M.
    Arvey, Aaron
    Rudensky, Alexander Y.
    Description

    Summary from GEO: "Regulatory T (Treg) cells, whose identity and function are defined by the transcription factor Foxp3, are indispensable for immune homeostasis. It is unclear whether Foxp3 exerts its Treg lineage specification function through active modification of the chromatin landscape and establishment of new enhancers or by exploiting a pre-existing enhancer landscape. Analysis of the chromatin...

    Subject
    Forkhead Transcription Factors
    Gene Expression
    Homeostasis/immunology
    T-Lymphocytes, Regulatory
    Access Rights
    Free to All