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  • Foxp3-dependent and -independent functions of peripherally-induced Treg cells [08075]

    Authors
    van der Veeken, Joris
    Campbell, Clarissa M.
    Pritykin, Yury
    Schizas, Michail
    8 more author(s)...
    Description

    Summary from GEO: "Regulatory T (Treg) cells expressing the lineage-defining transcription factor Foxp3 are essential for the maintenance of immune tolerance. Foxp3 expression can be induced in a subset of developing self-reactive thymocytes to yield thymic Treg (tTreg) cells, critical for tolerance against self-antigens. Alternatively, activation of mature naïve T cells under non-inflammatory conditions...

    Subject
    Forkhead Transcription Factors
    Immune Tolerance
    T-Lymphocytes, Regulatory
    Access Rights
    Free to All
  • Foxp3-dependent and -independent functions of peripherally-induced Treg cells [09748]

    Authors
    van der Veeken, Joris
    Campbell, Clarissa M.
    Pritykin, Yury
    Schizas, Michail
    8 more author(s)...
    Description

    Summary from GEO: "Regulatory T (Treg) cells expressing the lineage-defining transcription factor Foxp3 are essential for the maintenance of immune tolerance. Foxp3 expression can be induced in a subset of developing self-reactive thymocytes to yield thymic Treg (tTreg) cells, critical for tolerance against self-antigens. Alternatively, activation of mature naïve T cells under non-inflammatory conditions...

    Subject
    Forkhead Transcription Factors
    Immune Tolerance
    T-Lymphocytes, Regulatory
    Access Rights
    Free to All