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Single-cell RNA-sequencing reveals pervasive but highly cell type-specific genetic ancestry effects on the response to viral infection
- Authors
- Randolph, Haley E.Fiege, Jessica K.Thielen, Beth K.Cobb, M.S.3 more author(s)...
- Description
Description from GEO: "Humans show remarkable variation in susceptibility to infectious diseases as well as chronic inflammatory and autoimmune disorders. This heterogeneity arises partially from variation in the immune response, which is responsible for preventing and controlling infection. To better understand the major factors driving antiviral immune response differences, we used single-cell...
- Subject
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Autoimmune DiseasesInflammationInfluenza A virusInfluenza, HumanLeukocytes, MononuclearSingle-Cell Gene Expression Analysis
- Access Rights
- Free to All
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Influenza A response variation scripts
- Authors
- Randolph, Haley E.
- Description
Description from Zenodo: "Input files and scripts to run the main analyses for influenza A virus (IAV) response variation project. The pipeline is published on GitHub as "IAV_population-variation" (https://github.com/herandolph/IAV_population-variation). " Description from GitHub: "code necessary to reproduce the main analyses published in: Genetic ancestry effects on the response to viral infection...
- Subject
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Immunity, ActiveInfluenza A virusViral Infections
- Access Rights
- Free to All