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STAT4 promotes Bhlhe40 induction to drive protective IFN-g from natural killer cells during viral infection [STAT4 CUT&RUN]
- Authors
- Kim, HyunuSun, Joseph C.
- Description
Summary from GEO: "NK cells represent a cellular component of the mammalian innate immune system, and mount rapid responses against viral infection, including the secretion of the potent anti-viral effector cytokine IFN-g. Following mouse cytomegalovirus (MCMV) infection, Bhlhe40 was the most highly induced transcription factor in NK cells among the basic helix-loop-helix family. Bhlhe40 upregulation...
- Subject
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Basic Helix-Loop-Helix Transcription FactorsBinding sitesChromatin Immunoprecipitation SequencingInterferon-gammaInterleukin-12Interleukin-18Killer Cells, NaturalMouse CytomegalovirusSTAT4 Transcription Factor
- Access Rights
- Free to All
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STAT4 promotes Bhlhe40 induction to drive protective IFN-g from natural killer cells during viral infection [IL18R1KO RNA-seq]
- Authors
- Sheppard, SamLau, Colleen M.Kim, HyunuSun, Joseph C.
- Description
Summary from GEO: "NK cells represent a cellular component of the mammalian innate immune system, and mount rapid responses against viral infection, including the secretion of the potent anti-viral effector cytokine IFN-g. Following mouse cytomegalovirus (MCMV) infection, Bhlhe40 was the most highly induced transcription factor in NK cells among the basic helix-loop-helix family. Bhlhe40 upregulation...
- Subject
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Basic Helix-Loop-Helix Transcription FactorsInterferon-gammaInterleukin-12Interleukin-18Killer Cells, NaturalMouse CytomegalovirusRNA-SeqSTAT4 Transcription Factor
- Access Rights
- Free to All
-
STAT4 promotes Bhlhe40 induction to drive protective IFN-g from natural killer cells during viral infection [BHLHE40 CUT&RUN]
- Authors
- Kim, HyunuSun, Joseph C.
- Description
Summary from GEO: "NK cells represent a cellular component of the mammalian innate immune system, and mount rapid responses against viral infection, including the secretion of the potent anti-viral effector cytokine IFN-g. Following mouse cytomegalovirus (MCMV) infection, Bhlhe40 was the most highly induced transcription factor in NK cells among the basic helix-loop-helix family. Bhlhe40 upregulation...
- Subject
-
Basic Helix-Loop-Helix Transcription FactorsBinding sitesChromatin Immunoprecipitation SequencingInterferon-gammaInterleukin-12Interleukin-18Killer Cells, NaturalMouse CytomegalovirusSTAT4 Transcription Factor
- Access Rights
- Free to All
-
STAT4 promotes Bhlhe40 induction to drive protective IFN-g from natural killer cells during viral infection [RNA-Seq]
- Authors
- Lau, Colleen M.Kim, HyunuSun, Joseph C.
- Description
Summary from GEO: "NK cells represent a cellular component of the mammalian innate immune system, and mount rapid responses against viral infection, including the secretion of the potent anti-viral effector cytokine IFN-g. Following mouse cytomegalovirus (MCMV) infection, Bhlhe40 was the most highly induced transcription factor in NK cells among the basic helix-loop-helix family. Bhlhe40 upregulation...
- Subject
-
Basic Helix-Loop-Helix Transcription FactorsInterferon-gammaInterleukin-12Interleukin-18Killer Cells, NaturalMouse CytomegalovirusRNA-SeqSTAT4 Transcription Factor
- Access Rights
- Free to All
